Selective increase of brain dopamine induced by gamma-hydroxybutyrate
摘要:
Gamma-OH produces a marked and rapid increase in brain dopamine. Changes in brain norepinephrine and serotonin are much less pronunced. The increase in dopamine is limited to the areas of the extrapyramidal system. There is a temporal correlation between behavioural changes and dopamine increase induced by Gamma-OH. The mechanism of action of Gamma-OH in producing the dopamine rise is neither a MAO inhibition nor seems to be a stimulation of the dopamine synthesis.
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关键词:
Animals Rats Body Weight Citrate (si)-Synthase Protein Kinases RNA-Binding Proteins DNA-Binding Proteins Mitochondrial Proteins Nerve Tissue Proteins Transcription Factors
DOI:
10.1016/0024-3205(66)90261-X
被引量:
年份:
1966
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