Erythro-(E)-7-[3'-C 1 -3 alkyl-1'-(3",5"-dimethylphenyl)naphth-2'-yl]-3,5-dihydroxyhept-6-enoic acids and derivatives thereof
摘要:
Compounds of the formula ##STR1## wherein R 1 is C 1 -3 alkyl, and Z is ##STR2## wherein R 7 is hydrogen, R 8 or M, wherein R 8 is a physiologically acceptable and hydrolyzable ester group, and M is a pharmaceutically acceptable cation, the use thereof for inhibiting cholesterol biosynthesis and lowering the blood cholesterol level and, therefore, in the treatment of hyperlipoproteinemia and atherosclerosis, pharmaceutical compositions comprising such compounds and processes for and intermediates in the synthesis of such compounds.
展开
DOI:
US4804679 A
被引量:
年份:
1987
通过文献互助平台发起求助,成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用!