Nickel hypersensitivity. Nickel binding to amino acids and lymphocytes.

The nature of a protein hapten conjugate which could effect lymphocyte transformation in nickel hypersensitivity was investigated by subjecting the culture media employed to radiochromatographic analysis. Autoradiographic studies with 6...

F Hutchinson，TM Macleod，EJ Raffle - 《British Journal of Dermatology》

Nickel Hypersensitivity: Nickel Binding to Amino Acids and Lymphocytes

The nature of a protein hapten conjugate which could effect lymphocyte transformation in nickel hypersensitivity was investigated by subjecting the culture media employed to radiochromatographic analysis. Autoradiographic studies with 6...

JS T - 《Journal of Occupational & Environmental Medicine》

Nickel and DNCB Induce CCR7 Expression on Human Dendritic Cells Through Different Signalling Pathways: Role of TNF-α and MAPK

After application of haptens on the skin, immature dendritic cells (DC), also named Langerhans cells (LC), migrate to the draining lymph node to sensitize ...

Fanny，Boislève，Saadia，... - 《Journal of Investigative Dermatology》

Quantitative Estimation of the Reactivity of Normal and Hodgkin's Disease Lymphocytes with Thymidine-2-14C

SINCE lymphoid blood cells play an important part in the mediation of delayed hypersensitivity and homograft rejection1鈥 4, it is reasonable to expect that further understanding of these forms of immunological responsiveness will come fr...

ALAN，C.，AISENBERG - 《Nature》

Hypersensitivity to titanium osteosynthesis with impaired fracture healing, eczema, and T‐cell hyperresponsiveness in vitro: case report and review of the...

There are very few reports on hypersensitivity reactions in association with titanium-based materials so that the existence of allergy to titanium is still...

P Thomas，WD Bandl，S Maier，... - 《Contact Dermatitis》

MHC-Dependent and -Independent Activation of Human Nickel-Specific CD8+ Cytotoxic T Cells from Allergic Donors1

T lymphocytes are critical effectors in the pathogenesis of contact hypersensitivity. Nickel is the most common contact sensitizer in humans and nickel-spe...

C Moulon，D Wild，A Dormoy，... - 《Journal of Investigative Dermatology》

Topical cyclosporin A in nickel contact hypersensitivity: results of a preliminary clinical and immunohistochemical investigation.

Four out of eighteen (22%) patients with nickel contact sensitivity showed inhibition of skin patch test responses to the allergen in the presence of topic...

RD Aldridge，HF Sewell，G, King，... - 《Clinical & Experimental Immunology》

Skin hypersensitivity and in vitro lymphocytic reactivity to tuberculin in childhood

The mitogenic effect of old tuberculin was studied in cultures of peripheral lymphocytes from 113 children with a negative delayed dermal hypersensitivity ...

N Matsaniotis，C Tsenghi，C Economou-Mavrou，... - 《Journal of Pediatrics》