2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects approximately 1% of the adult population [1]. Although there is no cure, patients may reach a state of remission, which has become an achievable goal with optimal e...

 - 《Arthritis & Rheumatology》

Long-term impact of early treatment on radiographic progression in rheumatoid arthritis: A meta-analysis

Objective Although early initiation of disease-modifying antirheumatic drugs (DMARDs) is effective in controlling short-term joint damage in individuals wi...

A Finckh，MH Liang，CMV Herckenrode，... - 《Arthritis Care & Research》

A prediction rule for disease outcome in patients with recent-onset undifferentiated arthritis: how to guide individual treatment decisions.

Objective In patients with undifferentiated arthritis (UA), methotrexate is effective for inhibiting symptoms, structural damage, and progression to rheuma...

Annette H M van der Helm-van Mil，SL Cessie，HV Dongen，... - 《Arthritis & Rheumatology》

Validation of a prediction rule for disease outcome in patients with recent-onset undifferentiated arthritis: moving toward individualized treatment decisi...

Objective The decision to start disease-modifying antirheumatic drugs in patients with recent-onset undifferentiated arthritis (UA) is complicated by a var...

AH van，J Detert，CS Le，... - 《Arthritis & Rheumatology》

The Leiden Early Arthritis Clinic.

In 1993 a special Early Arthritis Clinic (EAC) was established at the Department of Rheumatology of the Leiden University Medical Center in order to detect...

AJ Van，JH van Bilsen，CF Allaart，... - 《Clinical & Experimental Rheumatology》

Biomarkers of inflammation and development of rheumatoid arthritis in women from two prospective cohort studies.

Objective To examine the association of biomarkers of inflammation with preclinical rheumatoid arthritis (RA). Methods A nested case-control study was per...

EW Karlson，LB Chibnik，SS Tworoger，... - 《Arthritis Rheum》

Improved treatment strategies reduce the increased mortality risk in early RA patients.

A higher mortality rate in patients with RA than in the general population has been reported in most series. Treatment strategies for RA have improved dram...

TWJ Huizinga - 《Rheumatology》

Prevalence of and predictive factors for sustained disease-modifying antirheumatic drug-free remission in rheumatoid arthritis: results from two large early arthritis cohorts.

Sustained DMARD-free remission in RA patients treated with conventional therapy is not uncommon. Symptom duration at presentation and the absence of autoantibodies are associated with sustained DMARD-free remission.

DVD Woude，A Young，K Jayakumar，... - 《Arthritis Rheum》

Gene-environment interaction between HLA-DRB1 shared epitope and heavy cigarette smoking in predicting incident rheumatoid arthritis.

Previous studies have reported an interaction between ever cigarette smoking and the presence of the human leukocyte antigen (HLA)-DRB1 shared epitope (SE)...

EW Karlson，SC Chang，J Cui，... - 《Annals of the Rheumatic Diseases》

The prognostic value of baseline erosions in undifferentiated arthritis

Introduction Undifferentiated arthritis (UA) has a variable disease course; 40 to 50% of UA patients remit spontaneously, while 30% develop rheumatoid arth...

MM Thabet，TW Huizinga… - 《Arthritis Research & Therapy》