Shinjulactone O, a new quassinoid from the root bark of Ailanthus altissima

阅读量:

75

作者:

XL YangYL YuanDM ZhangF LiWC Ye

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摘要:

A new quassinoid, shinjulactone O (1), and seven known quassinoids, were isolated from the 50% ethanol extract of the root bark of Ailanthus altissima. The structures of these compounds were determined based on spectroscopic methods including UV, IR, HR-ESI-MS, 1D and 2D NMR. Their cytotoxic activities were evaluated on the tumour cell lines MCF-7, MDA-MB-231, HepG2 and A549 cells, as well as the normal HUVEC line in vitro. Compounds 1–8 exhibited different levels of inhibitory activity against tumour cell lines.

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DOI:

10.1080/14786419.2014.909418

被引量:

9

年份:

2014

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来源期刊

Natural Product Research
September 2014

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