Friable tablet and process for manufacturing same
申请(专利)号:
US39849853A
申请日期:
12/16/1953
公开/公告号:
US2996431
公开/公告日期:
08/15/1961
申请(专利权)人:
Henry, Barry Richard
被引量:
摘要:
1. A pressed medicinal tablet which is resistant to breakage and chipping under impact but is capable of being crushed and disintegrated by the pressure of the thumb, said tablet being composed of about 30 to 70% by weight of hard, spheroidal medicinal pellets of about to 16 mesh, distributed in about 70 to 30% by weight of a comminuted matrix which is compacted into a hard, strongly cohesive mass which, in the form of a tablet composed wholly thereof, is highly resistant to being crushed with the thumb, said tablet on application of thumb pressure with a twisting motion being readily disintegrable, by reason of shearing forces transmitted by said pellets, into a substantially powdered matrix containing the spheroidal pellets in substantially undamaged condition.
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