Process for the preparation of paroxetine hydrochloride acetone solvate

阅读量:

11

申请(专利)号:

AU7542200

申请日期:

20001004

公开/公告号:

AU7542200A

公开/公告日期:

20010510

申请(专利权)人:

SMITHKLINE BEECHAM PLC

发明人:

ANDREW SIMON CRAIG

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摘要:

A process for preparing paroxetine hydrochloride acetone solvate, in which a solution of paroxetine base, or a salt of paroxetine with an organic acid, is treated with acetone and a solution of hydrogen chloride in a carrier solvent, and paroxetine hydrochloride acetone solvate is isolated as a crystalline solid.

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