Hemicentin 2 and Fibulin 1 are required for epidermal–dermal junction formation and fin mesenchymal cell migration during zebrafish development
摘要：
First analysis of Hmcn2 function in vertebrates. Hmcn2 acts in partial functional redundancy with Fibulin 1. Hmcn2/Fbln1 from internal sources regulate epidermal–dermal junction formation. Hmcn2/Fbln1-dependent ECM remodeling is required for mesenchymal cell migration. Tight interaction between Hmcn2 and Fbln1 is evolutionary highly conserved.
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关键词：
Zebrafish Blistering Epidermal–dermal junction Fin development Fin mesenchyme Cell migration Hemicentin Fibulin 1
DOI：
10.1016/j.ydbio.2012.06.023
被引量：
年份：
2012
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