摘要：

Anti-HIV agent (±)-calanolide A (1) has been synthesized. The key intermediate, chromene 5, was synthesized by the sequence of Pechmann reaction, acylation and chromenylation by 4,4-dimethoxy-2-methylbutan-2-ol. The anti-HIV activity for synthetic (±)-1 has been determined and compared with the natural product.

展开