Antimicrobial activities of Conyzolide and Conyzoflavone from Conyza canadensis
摘要：
Antibacterial and antifungal activities of the two isolated compounds from Conyza canadensis have been reported in the current study. The two isolated compounds i.e. Conyzolide (1) and Conyzoflavone (2) were tested against six bacterial and five fungal strains, employing hole diffusion and macrodilution methods. Both the compounds showed significant activities against the tested pathogens with special reference to E. coli, P. aeruginosa, S. aureus, Trichophytom longifusus, C. albicans, and C. glaberata. Conyzolide revealed comparatively better antibacterial activity against E. coli (minimum inhibitory concentration (MIC): 25 g/mL) in comparison to Conyzoflavone. However, in case of antifungal activities, Conyzoflavone exhibited superior antifungal activity against C. albicans (MIC: 10 g/mL) as compared to Conyzolide.
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关键词：
Bacteria Fungi Diterpenes Flavanones Plant Extracts Anti-Bacterial Agents Antifungal Agents Microbial Sensitivity Tests Dose-Response Relationship, Drug Molecular Structure
DOI：
10.3109/14756366.2010.528413
被引量：
年份：
2011
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