Yin Yang 1 (YY1): Regulation of Survivin and Its Role In Invasion and Metastasis
摘要：
The inhibitor of apoptosis protein survivin's threonine 34 to alanine (T34A) mutation abolishes a phosphorylation site for p34(cdc2)-cyclin B1, resulting in initiation of the mitochondrial apoptotic pathway in cancer cells; however, it has little known direct effects on normal cells. The possibility that targeting survivin in this way may provide a novel approach for selective cancer gene...
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DOI：
10.1615/CritRevOncog.2017020836
年份：
2017
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