摘要：

STR1## A compound of formula (I) or a pharmaceutically acceptable salt, ester or amide thereof, or a pharmaceutically acceptable solvate thereof, wherein R.sup.0 represents a substituted or unsubstituted aryl group; R.sup.1 represents hydrogen or an alkyl group; R.sup.2 represents a moiety of formula (a) wherein R.sup.4 and R.sup.5 each independently represent hydrogen, alkyl, hydroxyalkyl, cycloalkyl or R.sup.4 together with R.sup.5 represents (CH.sub.2).sub.n wherein n is 2, 3 or 4; T represents hydrogen, nitrile or a group --CO.R.sup.s wherein R. sup.s represents hydroxy, alkoxy or a group --NR.sup.t R.sup.u wherein R. sup.t and R.sup.u independently represent hydrogen, alkyl or R.sup.t and R.sup. u together with the nitrogen to which they are attached represent a saturated heterocyclic group; and R.sup.3 represents hydrogen, halogen, alkyl or alkoxy; a process for the preparation of such a compound, a pharmaceutical composition comprising such a compound and the use of such a compound in medicine.

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