A diminished number of nephrons has been proposed as one of the factors contributing to the development of primary hypertension.To test this hypothesis, we...
A diminished number of nephrons has been proposed as one of the factors contributing to the development of primary hypertension.To test this hypothesis, we...
A diminished number of nephrons has been proposed as one of the factors contributing to the development of primary hypertension.To test this hypothesis, we...
A letter to the editor is presented in response to the article "Nephron Number in Patients with Primary Hypertension," by G. Keller, G. Zimmer, G. Mall, E....
With improved immunosuppression and early allograft survival, chronic allograft nephropathy has become the dominant cause of kidney-transplant failure. We evaluated the natural history of chronic allograft nephropathy in a prospective s...
Background: A diminished number of nephrons has been proposed as one of the factors contributing to the development of primary hypertension. Methods: To te...
Catheter-related bacteremia occurred in 15 patients (13.0%) assigned to heparin only, as compared with 5 (4.5%) assigned to rt-PA (corresponding to ...
Original Article from The New England Journal of Medicine — The Effects of Dietary Protein Restriction and Blood-Pressure Control on the Progression of Ch...
The growth of blood vessels (a process known as angiogenesis) is essential for organ growth and repair. An imbalance in this process contributes to numerou...
Tubulointerstitial injury is an invariant finding in the chronically diseased kidney, irrespective of the type of disease or the compartment in which the d...
BACKGROUND: Renal thrombotic microangiopathy, typified by the hemolytic uremic syndrome, is associated with endothelial cell injury in which the presence o...
The mechanisms involved in plasticity in the nervous system are thought to support cognition, and some of these processes are affected during normal ageing...
Obesity is associated with proteinuria and could be a risk factor for end-stage renal disease (ESRD). However, few studies have examined the significance o...
A primary role for the kidney in the initiation and maintenance of has long been recognized, but the pathogenetic interactions among renal hemodynamics, ho...
Few cohort studies have focused on risk factors for end-stage renal disease (ESRD). This investigation evaluated the prognostic value of several potential ...
Mitochondria are the major organelles that produce reactive oxygen species (ROS) and the main target of ROS-induced damage as observed in various pathologi...
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