The role of mitochondria in apoptosis*.
摘要：
Mitochondria play key roles in activating apoptosis in mammalian cells. Bcl-2 family members regulate the release of proteins from the space between the mitochondrial inner and outer membrane that, once in the cytosol, activate caspase proteases that dismantle cells and signal efficient phagocytosis of cell corpses. Here we review the extensive literature on proteins released from the intermemb...
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DOI：
10.5483/BMBRep.2008.41.1.011
被引量：
年份：
2009
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