Surface Engineering and Patterning Using Parylene for Biological Applications
摘要:
Parylene is a family of chemically vapour deposited polymer with material properties that are attractive for biomedicine and nanobiotechnology. Chemically inert parylene "peel-off" stencils have been demonstrated for micropatterning biomolecular arrays with high uniformity, precise spatial control down to nanoscale resolution. Such micropatterned surfaces are beneficial in engineering biosensors and biological microenvironments. A variety of substituted precursors enables direct coating of functionalised parylenes onto biomedical implants and microfluidics, providing a convenient method for designing biocompatible and bioactive surfaces. This article will review the emerging role and applications of parylene as a biomaterial for surface chemical modification and provide a future outlook.
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关键词:
parylene micropatterning surface modification 2.2]paracyclophane biomaterial bioactive biomolecular nanobiotechnology microarray microfluidic
DOI:
10.3390/ma3031803
被引量:
年份:
2010
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