Two populations of Ia-like molecules on a human B cell line.
摘要：
Evidence is presented for two populations of Ia-like molecules on the human B cell line Raji. Two monoclonal antibodies, L203 and L227, are described. Both recognize nonpolymorphic determinants on B cell antigens. Both immunoprecipitate 34,000- and 28,000-dalton material from 125I-labeled extracts of Raji, but L227 precipitates 25,000-dalton material as well. Immunodepletion experiments confirm that the antibodies react with two different populations of molecules.
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关键词：
Humans B-Lymphocytes Cell Line Hybrid Cells Radioimmunoassay Antibodies Binding Sites, Antibody Histocompatibility Antigens Binding, Competitive Clone Cells
DOI：
10.4049/jimmunol.125.1.293
被引量：
年份：
1980
Semantic Scholar
Semantic Scholar
万方医学
NCBI
NCBI
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