Method and preparation for administration to the mucosa of the oral or nasal cavity

阅读量:

44

申请(专利)号:

US06/103558

申请日期:

19791213

公开/公告号:

US04250163A

公开/公告日期:

19810210

申请(专利权)人:

TEIJIN LTD

发明人:

T NagaiY MachidaY SuzukiH Ikura

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被引量:

429

摘要:

A method for administering a medicament which comprises adhering to the mucosa of the oral or nasal cavity a pharmaceutical preparation comprising(a) a water-swellable and mucosa- adhesive polymeric matrix comprising about 50 to about 95% by weight of a cellulose ether and about 50 to about 5% by weight of a homo- or copolymer of acrylic acid or a pharmaceutically acceptable salt thereof, and(b) dispersed therein, a pharmaceutically effective amount of the medicament,said preparation releasing continuously the medicament at a controlled rate; and causing the released medicament to be absorbed through the mucosa or enterally; said mucosa-adhesive preparation; and process for said preparation.

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1992
被引量:24

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