Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine
摘要:
Shows that a mutant allele of CCR-5, the chemokine receptor which functions as a co-receptor for macrophage-tropic (m-tropic) HIV-1 strains, is present at a high frequency in caucasian populations, but is missing from black populations in Western and Central Africa and from Japan. The link between HIV-1 and related viruses and co-receptors; The nature and extent of the CCR-5 mutation.
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年份:
1996
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