Suspension of nanospheres of lipophilic active principle stabilized with water-dispersible polymers

阅读量:

20

申请(专利)号:

10/060280

申请日期:

02/01/2002

公开/公告号:

US20020142017

公开/公告日期:

10/03/2002

申请(专利权)人:

SIMONNET JEAN-THIERRY

发明人:

JT Simonnet

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被引量:

323

摘要:

The present invention relates to a stable colloidal suspension consisting essentially: of a continuous aqueous phase, of nanospheres of lipophilic active principle with a mean particle size ranging from 0.01 to 1 μm, of at least one surfactant, and of colloidal particles, with a mean size ranging from 10 to 500 nm, of at least one water-dispersible polymer, and also to topical-application compositions containing such a colloidal suspension. The invention also relates to the use of water-dispersible polymers in the form of colloidal particles with a mean size ranging from 10 to 500 nm, to stabilize aqueous suspensions of nanospheres of lipophilic active principle, with a mean particle size ranging from 0.01 nm to 1 μm, against the recrystallization of the active principle.

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2013
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