Suspension of nanospheres of lipophilic active principle stabilized with water-dispersible polymers
申请(专利)号:
10/060280
申请日期:
02/01/2002
公开/公告号:
US20020142017
公开/公告日期:
10/03/2002
申请(专利权)人:
SIMONNET JEAN-THIERRY
被引量:
摘要:
The present invention relates to a stable colloidal suspension consisting essentially: of a continuous aqueous phase, of nanospheres of lipophilic active principle with a mean particle size ranging from 0.01 to 1 μm, of at least one surfactant, and of colloidal particles, with a mean size ranging from 10 to 500 nm, of at least one water-dispersible polymer, and also to topical-application compositions containing such a colloidal suspension. The invention also relates to the use of water-dispersible polymers in the form of colloidal particles with a mean size ranging from 10 to 500 nm, to stabilize aqueous suspensions of nanospheres of lipophilic active principle, with a mean particle size ranging from 0.01 nm to 1 μm, against the recrystallization of the active principle.
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