Plasma membrane-dependent activation of the 72-kDa type IV collagenase is prevented by complex formation with TIMP-2
摘要：
Secreted metalloproteases initiating proteolytic degradation of collagens and proteoglycans play a critical role in remodeling of the connective tissue. Activation of the secreted proenzymes and interaction with their specific inhibitors TIMP and TIMP-2 are responsible for regulation of enzyme activity in extracellular space. We have previously demonstrated that 92- and 72-kDa Type IV...
展开
关键词：
Humans Tumor Cells, Cultured Cell Membrane Fibrosarcoma Cyanogen Bromide Enzyme Precursors Collagenases Tissue Inhibitor of Metalloproteinase-2 Neoplasm Proteins Chromatography, Gel
DOI：
10.1016/0014-5793(93)81094-G
被引量：
年份：
1993
Elsevier
BMJ
Wiley
Semantic Scholar
万方医学
查看更多
NCBI
NCBI
Europe PMC
JBC
AACR
JBC
(全网免费下载)
ResearchGate
ResearchGate
(全网免费下载)
EBSCO
jcb.rupress.org
学术范
(全网免费下载)
钛学术
molbiolcell.org
emboj.embopress.org
d.scholar.cnki.net
cghjournal.org
biochemj.org
jleukbio.org
circres.ahajournals.org
jimmunol.org
mendeley.com
学术范
jcs.biologists.org
www.socolar.com
钛学术
(全网免费下载)
通过文献互助平台发起求助，成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
