摘要：

Lymphoproliferative disorders can involve the lungs in 3 ways: (1) by hematogenous spread of non-Hodgkin's lymphoma (NHL) or Hodgkin's disease (HD), (2) by contiguous invasion from a hilar or mediastinal site of nodal lymphoma, or (3) by primary pulmonary/airway involvement. Lymphomas occurring primary to the lung are rare and account for <1 % of all primary pulmonary neoplasms and all extranodal non-Hodgkin's lymphomas (NHLs). The clinical presentation and radiologic findings vary according to the location of the main lesion, which can occur mostly in the lung parenchyma or, as reported in rare cases, in the large airways. The diagnosis relies on the histologic evaluation of tissue samples and the confirmation of the presence of a lymphoid clonal proliferation by ancillary studies. The vast majority of primary pulmonary lymphomas are marginal zone B cell lymphomas of mucosa-associated lymphoid tissue (MALT). Other less common types of lymphoma occurring primary to the lung include diffuse large B cell lymphoma, lymphomatoid granulomatosis, anaplastic large cell lymphoma, and lymphoproliferative disorders associated with immunosuppressed states.

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