Studies toward the construction of substituted piperidine-2-ones and pyridine-2-ones from Baylis–Hillman adducts: discovery of a facile synthesis of 5-methyl-4-oxo-6-aryl-3-aza-bicyclo[3.1.0]hexane-1-carboxylates
摘要：
Studies toward the construction of functionalized piperidone derivatives from derivatives of Baylis–Hillman adducts are described. Interestingly the 6-oxo-4-aryl-piperidine-3-carboxylates generated during the study serve as precursor for the facile synthesis of 4-oxo-6-aryl-3-aza-bicyclo[3.1.0]hexane-1-carboxylates.
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关键词：
Baylis–Hillman Piperidine-2-one DBU 4-Oxo-3-aza-bicyclo[3.1.0]hexane 3-Methylene-piperidine-2,6-dione
DOI：
10.1016/j.tet.2006.06.099
被引量：
年份：
2006
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