Functional and morphological assessment of a standardized rat sciatic nerve crush injury with a non-serrated clamp.

We have recently described the sequence of functional and morphologic changes occurring after a standardized sciatic nerve crush injury. An 8-week post-inj...

AS Varejão，AM Cabrita，MF Meek，... - 《J Neurosci Methods》

Nerve conduits and growth factor delivery in peripheral nerve repair

Peripheral nerves possess the capacity of self-regeneration after traumatic injury. Transected peripheral nerves can be bridged by direct surgical coaptati...

LA Pfister，M Papalo?Zos，HP Merkle，... - 《Journal of the Peripheral Nervous System》

Outcome measures of peripheral nerve regeneration

Animal models of nerve compression, crush, and transection injuries of peripheral nerves have been subject to extensive study in order to understand the me...

MD Wood，SWP Kemp，C Weber，... - 《Annals of Anatomy》

Choosing the correct functional assay: a comprehensive assessment of functional tests in the rat.

While there are several ways to quantify peripheral nerve regeneration; the true measure of successful outcome is functional recovery. Functional tests are...

CM Nichols，TM Myckatyn，SR Rickman，... - 《Behavioural Brain Research》

Reinnervation of the tibialis anterior following sciatic nerve crush injury: A confocal microscopic study in transgenic mice

Transgenic mice whose axons and Schwann cells express fluorescent chromophores enable new imaging techniques and augment concepts in developmental neurobio...

CK Magill，A Tong，D Kawamura，... - 《Experimental Neurology》

Axonal Regeneration and Neuronal Function Are Preserved in Motor Neurons Lacking -Actin In Vivo

The proper localization of -actin mRNA and protein is essential for growth cone guidance and axon elongation in cultured neurons. In addition, decreased le...

TR Cheever，EA Olson，JM Ervasti - 《Plos One》

Sciatic nerve injury: A simple and subtle model for investigating many aspects of nervous system damage and recovery

Sciatic nerve injury has been used for over a century to investigate the process of nerve damage, to assess the absolute and relative capacity of the centr...

LE Savastano，SR Laurito，MR Fitt，... - 《Journal of Neuroscience Methods》

Possible mechanism of flicking-induced short-term plasticity in retinal cone-LHC synapse: a computational study

In retinal cone-HC synapse, it has been found that repetitive stimulation could induce postsynaptic short-term responsiveness enhancement. However, the det...

X Jin，JF Hu，PJ Liang - 《Biological Cybernetics》

Functional recovery following peripheral nerve injury in the transgenic Thy1‐GFP rat

Transgenic mice have been previously used to assess nerve regeneration following peripheral nerve injury. However, mouse models are limited by their small ...

SWP Kemp，PD Phua，KN Stanoulis，... - 《Journal of the Peripheral Nervous System Jpns》

Detection of subtle neurological alterations by the Catwalk XT gait analysis system

Background A new version of the CatWalk XT system was evaluated as a tool for detecting very subtle alteration in gait based on higher speed sample rate; t...

YJ Chen，FC Cheng，ML Sheu，... - 《Journal of Neuroengineering & Rehabilitation》