摘要：

Objective To study the relationships between the expressions of the density of microvessels (MVD) of the tumors and the clinicopathologic features, disease - free survival rates in endometrial carcinoma. Methods Specimens from 34 cases of endometrial carcinoma were studied by immunohistochemical stainings with monoclonal antibodies to MVD. Results MVD high- density rates were found higher in the following cases, tumor size ^2 cm than in that 2 cm (84.62% vs 66.67% , P =0.000 4) , stage Ⅲ than in stage Ⅰ-Ⅱ (100.00% vs 74.74% , P = 0.001 0) and age 50 than in age≥50 (100.00% vs 78.33% , P = 0.016 0) . 3 cases with lymph node metastasis all showed high- density MVD. There was no significant correlation between MVD and histologic grade or disease - free survival rate. Conclusions MVD was associated with tumor growth , metastasis and was age - dependent in endometrial carcinoma.

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