Intrathecal morphine in mice: A new technique
摘要:
A simple, rapid technique for intrathecal injections by lumbar puncture in unanesthetized mice is described. Intrathecal [ 3 H]morphine base was not found in significant quantitities in either the midbrain or forebrain. Submicrogram quantities of morphine sulfate induced Straub tail response and tail-flick analgesia. These effects were dose related and antagonized by subcutaneous naloxone.
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DOI:
10.1016/0014-2999(80)90515-4
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年份:
1980
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来源期刊
European Journal of Pharmacology
17 October 1980
引用走势
2010
被引量:201
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