Notch Signaling in Cancer

阅读量:

61

作者:

EJ AllenspachI MaillardJC AsterWS Pear

展开

摘要:

Notch signaling plays a key role in the normal development of many tissues and cell types, through diverse effects on differentiation, survival, and/or proliferation that are highly dependent on signal strength and cellular context. Because perturbations in the regulation of differentiation, survival, and/or proliferation underlie malignant transformation, pathophysiologic Notch signals potentially contribute to cancer development in several different ways.

展开

DOI:

10.4161/cbt.1.5.159

被引量:

1013

年份:

2002

相似文献

参考文献

引证文献

来源期刊

引用走势

2012
被引量:118

辅助模式

0

引用

文献可以批量引用啦~
欢迎点我试用!

引用