RasActivation byInsulin andEpidermal GrowthFactor through Enhanced Exchange ofGuanine Nucleotides on p2lras
摘要：
Recently, it was shown that rottlerin inhibits insulin-stimulated glucose uptake and reduces intracellular adenosine triphosphate (ATP) levels in 3T3-L1 adipocytes, suggesting that these two events are causally linked. However, several other reports show that ATP-depletion induces glucose uptake in both muscle cells and adipocytes. In the present study, the mechanism of inhibition by rottlerin...
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DOI：
10.1128/mcb.13.1.155
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