"Designer Acids": Combined Acid Catalysis for Asymmetric Synthesis
摘要:
Lewis and Br?nsted acids can be utilized as more-effective tools for chemical reactions by sophisticated engineering (designer acids). The ultimate goal of such designer acids is to form a combination of acids with higher reactivity, selectivity, and versatility than the individual acid catalysts. One possible way to take advantage of such abilities may be to apply a combined acids system to the catalyst design. The concept of combined acids, which can be classified into Br?nsted acid assisted Lewis acid (BLA), Lewis acid assisted Lewis acid (LLA), Lewis acid assisted Br?nsted acid (LBA), and Br?nsted acid assisted Br?nsted acid (BBA), can be a particularly useful tool for the design of asymmetric catalysis, because combining such acids will bring out their inherent reactivity by associative interaction, and also provide more-organized structures that allow an effective asymmetric environment.
展开
DOI:
10.1002/anie.200460394
被引量:
年份:
2005
相似文献
参考文献
引证文献
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用!