Expression of vascular endothelial growth factor in human adrenals.
摘要:
Angiogenesis is an important component in many biological processes and also in pathologic conditions including neoplastic diseases. Vascular endothelial growth factor (VEGF) is a secreted endothelial cell-specific growth factor, which is induced by tissue hypoxia and is angiogenic in vivo. Adrenal gland is a well-vascularized organ, and the roles of VEGF in normal adrenal and in adrenal tumorigenesis is not well characterized. We therefore investigated VEGF mRNA expression in normal human adrenals and in cultured adrenocortical cells.
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关键词:
Humans Cells, Cultured Tetradecanoylphorbol Acetate Bucladesine Vascular Endothelial Growth Factor A Dose-Response Relationship, Drug Vascular Endothelial Growth Factors Adrenal Glands Lymphokines Endothelial Growth Factors
DOI:
10.3109/07435800009048610
被引量:
年份:
2000
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