Solubility parameter based drug delivery system and method for altering drug saturation concentration
申请(专利)号：
IE19920002897
申请日期：
1992-12-14
公开/公告号：
IE922897A1
公开/公告日期：
1994-06-15
申请(专利权)人：
NOVEN PHARMACEUTICALS
被引量：
摘要：
A blend of at least two polymers, or at least one polymer and a soluble polyvinylpyrrolidone, in combination with a drug provides a pressure-sensitive adhesive composition for a transdermal drug delivery system in which the drug is delivered from the pressure-sensitive adhesive composition and through dermis when the pressure-sensitive adhesive composition is in contact with human skin. According to the invention, soluble polyvinylpyrrolidone can be used to prevent crystallization of the drug, without affecting the rate of drug delivery from the pressure-sensitive adhesive composition.
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