Intraspecific chemical variation within the crustose lichen genus Haematomma: anthraquinone production in selected cultured mycobionts as a response to stress and nutrient supply

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摘要：

The mycobionts isolated from selected species of Haematomma (Haematomma africanum, Haematomma fenzlianum, Haematomma flourescens, Haematomma persoonii, Haematomma stevensiae) have been successfully cultured. The chemical profile of the mycobionts could be effectively influenced and modulated by varying the composition of the nutrient medium using alternative carbohydrates (glucose, sucrose, and polyols). Under artifical laboratory conditions and simulated environmental stress (exposure to UV light, desiccation, and lower temperatures) the mycobionts began producing typical secondary lichen metabolites after an incubation time of 5-6 months. Modified Lilly and Barnett medium (LBM) and Murashige Skoog Medium favoured the production of depsides such as sphaerophorin and isosphaeric acid. Surprisingly, the mycobiont from H. stevensiae in modified MS medium produced two anthraquinones in the mycelia, haematommone at the base and russulone in the upper parts of the

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关键词：

Lichens Secondary chemistry Polyketides Mycobiont cultures Haematommone Russulone

DOI：

10.1016/j.gyobfe.2006.10.027

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年份：

2009