Asymmetric Iminium Ion Catalysis with a Novel Bifunctional Primary Amine Thiourea: Controlling Adjacent Quaternary and Tertiary Stereocenters

来自 Wiley

阅读量:

42

摘要:

,β-unsaturated aldehydes, generating valuable chiral scaffolds with contiguous quaternary and tertiary stereocenters (see scheme). For the first time, a chiral primary amine thiourea catalyst has been successfully applied for iminium-ion activation.

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DOI:

10.1002/chem.200802466

被引量:

473

年份:

2009

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2010
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