Electron microscope study of palate fusion in mouse embryos.
摘要:
An electron microscope study of palatal fusion in 14 1 2- day mouse embryos was done. The epithelium of the palatine processes was examined prior to, during, and immediately following fusion. Significant findings include the following. In the prefusion palatine process, the basement lamina underlying the epithelium was discontinuous and there were epithelial cell projections into the connective tissue space. At the time of fusion no membrane specializations were found on contacting surface cells of opposing palatal processes. There was evidence, however, of true adhesion between epithelia of opposing processes, but no extracellular "sticky substance" was demonstrable. Immediately following palatal fusion there was widespread evidence of cell death in the midline epithelial seam. Dead epithelial cells were phagocytized by neighboring epithelial cells in the fusion line and by invading connective tissue cells.
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DOI:
10.1016/0012-1606(68)90038-9
被引量:
年份:
1968
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