IV administration for insoluble medicaments

阅读量:

43

公开/公告号:

US5399363 A

公开/公告日期:

Mar 21, 1995

发明人:

GG LiversidgeE LiversidgePP Sarpotdar

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被引量:

761

摘要:

Dispersible particles consisting essentially of a crystalline anticancer agent having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 1000 nm. Anticancer compositions comprising the particles exhibit reduced toxicity and/or enhanced efficacy, and can be administered by IV bolus injection.

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2011
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