Coat Proteins and Vesicle Budding
摘要：
The trafficking of proteins within eukaryotic cells is achieved by the capture of cargo and targeting molecules into vesicles that bud from a donor membrane and deliver their contents to a receiving compartment. This process is bidirectional and may involve multiple organelles within a cell. Distinct coat proteins mediate each budding event, serving both to shape the transport vesicle and to select by direct or indirect interaction the desired set of cargo molecules. Secretion, which has been viewed as a default pathway, may require sorting and packaging signals on transported molecules to ensure their rapid delivery to the cell surface.
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关键词：
Organelles Coated Vesicles Endoplasmic Reticulum Golgi Apparatus Cell Membrane Intracellular Membranes Proteins Membrane Proteins Clathrin Coatomer Protein
DOI：
10.1126/science.271.5255.1526
被引量：
年份：
1996
Semantic Scholar
万方医学
掌桥科研
dx.doi.org
Europe PMC
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