Altered polypeptides with increased half-life

阅读量:

30

公开/公告号:

US5739277 A

公开/公告日期:

2006-02-14

被引量:

517

摘要:

Polypeptides that are cleared from the kidney and do not contain in their original form a Fc region of an IgG are altered so as to comprise a salvage receptor binding epitope of an Fc region of an IgG and thereby have increased circulatory half-life.

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2011
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