Altered polypeptides with increased half-life
公开/公告号:
US5739277 A
公开/公告日期:
2006-02-14
被引量:
摘要:
Polypeptides that are cleared from the kidney and do not contain in their original form a Fc region of an IgG are altered so as to comprise a salvage receptor binding epitope of an Fc region of an IgG and thereby have increased circulatory half-life.
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