摘要：

This article reports that a newly developed "on-water" protocol is characterized by short reaction times, and the products are easy to isolated. Diels-Alder reactions in organic chemistry, often used for the synthesis of six-membered rings, may be greatly accelerated in water. Similar results were obtained for other types of simple organic reactions. Subsequent mechanistic studies have established that this behaviour results from enforced hydrophobic interactions and stabilization of the activated complex by hydrogen-bond formation. The reactants are initially floating on the surface of water, hence the "on water" designation, and the reaction product is often produced in a pure state under or on the water, allowing it to be easily isolated by phase separation or filtration.

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