Br酶nsted acid-catalyzed efficient Strecker reaction of ketones, amines and trimethylsilyl cyanide
摘要：
A general method for the one-pot, three-component Strecker reaction of ketones was developed using Br酶nsted acids as organocatalysts. A series of 伪-aminonitriles were obtained in good to excellent yields (79鈥). A preliminary extension to a catalytic enantioselective three-component Strecker reaction of ketones (up to 40% ee) is also described.
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DOI：
10.1002/chin.201031082
被引量：
年份：
2010
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