Laser-induced acoustic desorption/atmospheric pressure chemical ionization of compounds
申请(专利)号:
US201113080597
申请日期:
2011-04-05
公开/公告号:
US8344319B2
公开/公告日期:
2013-01-01
申请(专利权)人:
HILKKA I. KENTTAMAA;DAVID JESSE BORTON, II;JINSHAN GAO;ZHICHENG JIN;BENJAMIN CURTIS OWEN
被引量:
摘要:
The present disclosure provides a novel system and method for evaporating and ionizing compounds comprising an LIAD source and an ionization source that operates at atmospheric pressure. This system is readily adaptable for use with most commercially available mass spectrometers. Ionization sources include Atmospheric Pressure Chemical Ionization sources (APCI) and Atmospheric Pressure Photo Ionization (APPI) sources. The ionization sources are positioned such that the analyte desorbing from the surface of the LIAD is fed into the ion stream produced by the ionization source and ionized analyte and ionized fragments of the analyte are fed into the sample inlet of a mass spectrometer. These systems allow for the mass spectrometric analysis of non-polar compounds that lack readily ionizable functional groups, such as saturated and unsaturated hydrocarbons and compounds with medium to low polarity, as well as hydrocarbon mixtures, such as petroleum.
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