Expression of Cyclooxygenase2 in Human Lung Carcinoma1

阅读量:

100

作者:

H WolffK SaukkonenS AnttilaA KarjalainenH Vainio

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摘要:

Polymorphism of CYP2D6 gene encoding for debrisoquine hydroxylase was determined genotypically for 94 controls and 77 lung cancer patients using a polymerase chain reaction-based application. Both of the point mutations that give rise to deficient alleles of the CYP2D6 gene are detectable by this method. Out of the 94 healthy controls, 3 individuals (3.2%) had poor metabolizer (PM) genotypes,...

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DOI:

10.1093/annonc/mdr431

被引量:

1600

年份:

1998

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来源期刊

Cancer Research
1998/12/01

引用走势

2004
被引量:161

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