摘要：

Presents a study which shows that the mitochondrial protein Smac/DIABLO performs a critical function on apoptosis, or programmed cell death. How Smac/DIABLO promotes the enzymatic activity of mature caspase-3 in addition to the activation of procapsase-3; Importance of the interaction between Smac/DIABLO and apoptosis protein inhibitors; Structure of Smac/DIABLO; Role of the amino-terminal amino acids of Smac/DIABLO.

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