Inhibition of histidine decarboxylase by imidazole derivatives
摘要:
A series of 4-imidazolylmethyl arylsulfides, sulfoxides, and sulfones and two carbon isosteres of 4-imidazolylmethylphenyl sulfide (I) were synthesized and tested for inhibition of histidine decarboxylase from rat stomach. None of these analogs of I met the criterion of a potent and specific inhibitor of histidine decarboxylase.
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关键词:
Imidazoles, 4-substituted - synthesis and evaluation for inhibition of histidine decarboxylase Histidine decarboxylase - inhibition, synthesis and evaluation of 4-substituted imidazoles Structure - activity relationships - synthesis and evaluation of 4-substituted imidazoles for inhibition of histidine decarboxylase
DOI:
10.1002/jps.2600700334
被引量:
年份:
1981
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