Heroin reward is dependent on a dopaminergic substrate
摘要:
The rewarding property of heroin was blocked by pretreatment with either naloxone or pimozide, suggesting that this opiate-receptor mediated effect is dependent on a dopaminergic substrate. The involvement of a dopaminergic mechanism in this effect supports the notion that opiates and other sources of reward activate a similar neural substrate.
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DOI:
10.1016/0024-3205(81)90519-1
被引量:
年份:
1981
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