New briaranes from the Taiwanese gorgonian Junceella juncea.
摘要:
In addition to the known junceelolide C (4), three new briaranes, juncenolides B (1), C (2), and D (3), have been isolated from the extract of a red Gorgonian collected in Taiwan. The structures of 1-3 were elucidated on the basis of FABMS and 2D NMR techniques including COSY, HMQC, HMBC, and NOESY experiments. Among them, compound 2 exhibited mild cytotoxicity against (HEPA 59T/VGH) and oral epidermoid (KB) cells.
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关键词:
KB Cells Tumor Cells, Cultured Animals Humans Cnidaria Liver Neoplasms Diterpenes Lactones Nuclear Magnetic Resonance, Biomolecular Drug Screening Assays, Antitumor
DOI:
10.1021/np0203584
被引量:
年份:
2003
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