Abstract 5869: Resistance mechanism against trastuzumab in HER2-positive cancer cells and its negation by Src inhibition
摘要：
Background: In biliary tract cancer (BTC), no molecular therapeutic target has been validated so far. Therefore, cytotoxic chemotherapy is the mainstay of treatment of advanced BTC and the prognosis is poor and there is a huge unmet medical need. Src is a nonreceptor tyrosine kinase involved in the crosstalk and mediation of many signaling pathways that promote cell proliferation, invasion and...
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DOI：
10.1158/1538-7445.AM2017-5869
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年份：
2017
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来源期刊
Cancer Research
2017/07/01
引用走势
2018
被引量：7
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