Recognition and Reaction of Metallointercalators with DNA

来自 万方

阅读量:

113

作者:

KE ErkkilaDT OdomJK Barton

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摘要:

The design of small complexes that bind and react at specific sequences of DNA becomes important as we begin to delineate, on a molecular level, how genetic information is expressed. A more complete understanding of how to target DNA sites with specificity will lead not only to novel chemotherapeutics but also to a greatly expanded ability for chemists to probe DNA and to develop highly sensitive diagnostic agents.

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DOI:

10.1021/cr9804341

被引量:

2571

年份:

1999

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来源期刊

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2010
被引量:273

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