A Highly Active 4㏒iloxyproline Catalyst for Asymmetric Synthesis

阅读量:

38

作者:

Y HayashiJ YamaguchiK HibinoT SumiyaH Koshino

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摘要:

trans-4-tert-Butyldimethylsiloxy-L-proline displays a greater catalytic activity than the parent proline without compromising the enantioselectivity, which widens the substrate scope in the -aminoxylation of carbonyl compounds, as well as O-nitroso-aldol/Michael, and Mannich reactions.

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DOI:

10.1002/adsc.200404166

被引量:

391

年份:

2004

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