Pharmaceutical preparations containing cyclodextrin derivatives
The invention comprises pharmaceutical preparations consisting generally of a drug with a substantially low water solubility and an amorphous, water-soluble cyclodextrin-based mixtures. In these preparations a stable amorphous state can ...
J Pitha - US
2-[8-quinolinyl]-sulphinyl-1H-benzimidazole
google_ad_client = 'pub-1586334167197709'; google_ad_channel = '644+871+557+345+447'; google_feedback = 'on'; google_ad_width = 336; google_ad_height = 280...
AE Brandstrom，PL Lindberg，B Wallmark - US
Gastric acid secretion inhibiting substituted 2-(2-benzimidazolyl)-pyridines, pharmaceutical preparations containing same, and method for inhibiting gastric acid secretion
The present invention relates to novel compounds of the formula ##STR1## wherein R 1 and R 2 are the same or different and are each hydrogen, alkyl, halogen, carbomethoxy, carbethoxy, alkoxy, or alkanoyl, R 6 is hydrogen, methyl or et...
UK Junggren，SE Sjostrand - US
Method for preparing a pharmaceutically active enantiomeric or enantiomerically enriched sulfoxide compound by enantioselective bioreduction of a racemate sulfoxide compound
A compound of formula (II), either as a single enantiomer or in an enantiomerically enriched form ##STR1## wherein: ##STR2## and ##STR3## (wherein N in the benzimidazole moiety of Het.sub.2 means that one of the carbon atoms substituted ...
D Graham，R Holt，P Lindberg，... - US
Base addition salts of omeprazole
Novel salts of omeprazole with Li + , Na + , K + , Mg 2+ , Ca 2+ , Ti 4+ , N + (R 1 ) 4 or ##STR1## as cation; processes for their preparation thereof, pharmaceutical compositions containing such salts and their use in medicine.
AE Brandstrom - US
Complexing low water solubility drug with water-soluble mixture
The invention comprises pharmaceutical preparations consisting generally of a drug with a substantially low water solubility and an amorphous, water-solubl...
J Pitha - US
Pharmaceutical formulations of acid labile substances for oral use
Pharmaceutical preparation containing an acid labile compound together with an alkaline reacting compound or an alkaline salt of an acid labile compound optionally together with an alkaline compound as the core material, one or more subc...
Lvgren Kurt Ingmar，Pilbrant Ake Gunnar，Y Mitsuru，... - CA
Preparation of pharmaceutically active compounds by biooxidation
Enantiomeric or enantiomerically enriched H.sup.+ K.sup.+ ATPase inhibiting pyridinylsulfinyl--benzimidazoles are prepared using microorganisms or microbial enzyme systems to enantioselectively biooxidize corresponding prochiral sulfide ...
R Holt，P Lindberg，C Reeve，... - US
Pharmaceutical bacteriocin compositions and methods for using the same
Compositions comprising lanthionine-containing bacteriocins such as nisin act as bactericides under conditions such as those found in the gastrointestinal tract. In a preferred embodiment pharmaceutical preparations containing the compos...
P Blackburn，Projan, Steven J，Goldberg, Edward B - US
Omeprazole, antisecretory agents
Pharmaceutical preparation containing omeprazole together with an alkaline reacting compound or an alkaline salt of omeprazole optionally together with an ...
KI Lovgren，AG Pilbrant，M Yasumura，...
