Prenyl proteins in eukaryotic cells: a new type of membrane anchor
摘要:
Recent studies have indicated that eukaryotic cells contain proteins that are post-translationally modified by long-chain, thioether-linked prenyl groups. These proteins include yeast mating factors, ras proteins and nuclear lamins. The modification occurs on a cysteine residue near the C terminus and appears to initiate a set of additional protein modification reactions that promote attachment of the proteins to specific membranes.
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关键词:
Cells Cell Membrane Eukaryotic Cells Animals Humans Polyisoprenyl Phosphates Peptides Proteins Proto-Oncogene Proteins Nuclear Proteins
DOI:
10.1016/0968-0004(90)90213-U
被引量:
年份:
1990
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