Selective inhibition of ras-dependent transformation by a farnesyltranferase inhibitor.
摘要:
Reports on the selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor in cells. Farnesylation of the cysteine residue located in a carboxyl-terminal tetrapeptide; Anticancer agents for tumors in which Ras contribures to transformation.
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年份:
1993
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1999
被引量:53
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